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International Journal of Clinical Biology and Biochemistry

Vol. 5, Issue 2, Part A (2023)

Diagnostic importance of lactate-albumin ratio in terms of mortality in patients with postoperative Sepsis

Author(s):

Recai ACI, Adem Keskin, Murat Ari and Melek Bilgin

Abstract:

We designed our study to investigate the relationship between lactate-albumin ratio and mortality in inpatients in the intensive care department due to postoperative sepsis. Inpatients in the intensive care department due to postoperative sepsis were included in our study. Clinical and demographic data of the inpatients were obtained from hospital information management system. The blood gas lactate and albumin values of all inpatients in the intensive care department due to sepsis were measured. The lactate albumin ratios, some biochemical and hematological parameters of patients with and without mortality were compared. ROC curve statistical analyzes were performed to found the predictive diagnostic value of lactate-albumin ratio in predicting mortality. The lactate-albumin ratio and lymphocyte levels of the not-survival patients were higher than the lactate-albumin ratio and lymphocyte levels of the patients who survived. The area under the ROC curve for lactate-albumin ratio in predicting mortality between survival and non-survival by ROC analysis was 0.695 (95% CI: 0.522-0.756) (p=0.025). As a result of the analysis, it was determined that lactate-albumin ratio was positively related with lactate, neutrophil and monocyte values, and negatively correlated with albumin and pO2 values.
The lactate-albumin ratio is an important determinant of mortality in inpatients with postoperative sepsis. Due to the hospitalization of the patient, close monitoring of the lactate-albumin ratio may change the treatment management and clinical results.
 

Pages: 16-20  |  348 Views  104 Downloads


International Journal of Clinical Biology and Biochemistry
How to cite this article:
Recai ACI, Adem Keskin, Murat Ari and Melek Bilgin. Diagnostic importance of lactate-albumin ratio in terms of mortality in patients with postoperative Sepsis. Int. J. Clin. Biol. Biochem. 2023;5(2):16-20. DOI: 10.33545/26646188.2023.v5.i2a.44
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